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FLASH GENE
Symbol CTPS2 contributors: mct - updated : 28/11/2008
HGNC name CTP synthase II
HGNC id 2520
Location Xp22.2      Physical location : 16.606.123 - 16.731.059
Synonym name
  • cystidine triphosphate (CTP) synthase 2
  • UTP--ammonia ligase 2
    • Synonym symbol(s) DKFZp686C17207, FLJ43358, MGC32997
    EC.number 6.3.4.2
    DNA
    TYPE functioning gene
    STRUCTURE 124.94 kb     19 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    19 - 3844 65 586 - 2006 17081983
    19 - 3947 - 586 - 2006 17081983
    19 - 4334 - 586 - -
    EXPRESSION
    Type widely
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Endocrineadrenal gland   highly
    Lymphoid/Immunelymph node   highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • two major phosphorylation sites, Ser(568) and Ser(571)
    • HOMOLOGY
    Homologene
    FAMILY
  • CTP synthase family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    basic FUNCTION
  • converting uridine triphosphate (UTP) to CTP
  • generates the CTP required for the synthesis of nucleic acids and membrane phospholipids
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    text basic converting urideme triphosphate (UTP)
    PATHWAY
    metabolism purine/pyrimidine
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    Other phosphorylated by mammalian protein kinase A
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS