basic FUNCTION
| playing an essential role for normal transcription during meiosis |
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promotes germ-cell-specific patterns of polyadenylation by binding to different downstream sequence elements  |
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CSTF2, CSTF2T differ in their affinities for specific RNA sequences, and the region C-terminal to the RBDs (RNA-binding domains) is mportant in RNA sequence recognition  |
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required not only for expression of genes involved in morphological differentiation of spermatids but also for genes having products that function during interaction of motile spermatozoa with eggs  |
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necessary for spermatogenesis and fertilization  |
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its function is primarily to support spermatogenesis, but only incidentally to support immune cell function  |
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plays likely a role in 3prime end determination and transcription termination for a large range of germ cell-expressed genes  |
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functional overlap and specificity of CSTF2, CSTF2T mRNA 3 prime processing factors and provided new insights into the regulatory mechanisms of mRNA 3 prime processing  |