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FLASH GENE

Symbol

CSN3

contributors: npt/ - updated : 03-02-2004

HGNC name	casein kappa
HGNC id	2446

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	4q13.3      Physical location : 71.108.332 - 71.117.143
Synonym symbol(s)	CSN10, CSNK, KCA, CASK

DNA

TYPE	functioning gene
SPECIAL FEATURE	component of a cluster, opposite orientation
text	oriented in opposite orientation to CSN2 gene
STRUCTURE	8.81 kb     5 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

confirmed

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_005212 5 - 834 NP_005203 - 182 - -

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Reproductive female system breast

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Epithelial secretory glandular

cell lineage
cell lines
fluid/secretion	milk

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

conjugated

GlycoP , PhosphoP

HOMOLOGY

interspecies

ortholog to murine Csnk

Homologene

FAMILY

kappa-casein family

CATEGORY

unknown/unspecified

SUBCELLULAR LOCALIZATION

extracellular

basic FUNCTION	playing a role in the stabilization of the micelle structure
	preventing casein precipitation in milk

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

heteromultimers composed of alpha-S1 casein and kappa casein linked by disulfide bonds

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS