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FLASH GENE
Symbol CSN2 contributors: - updated : 03-02-2004
HGNC name casein beta
HGNC id 2447
Location 4q13.1-q21.1      Physical location : 70.820.974 - 70.826.726
Synonym symbol(s) CASB
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster, opposite orientation
text oriented in the opposite direction to CSN1S1 and CSN3 genes
STRUCTURE 5.00 kb     7 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivefemale systembreast   
 female systembreast   
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandular  
cell lineage
cell lines
fluid/secretion milk
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated GlycoP , PhosphoP
HOMOLOGY
interspecies ortholog to murine Csnb
Homologene
FAMILY beta-casein family
CATEGORY structural protein
SUBCELLULAR LOCALIZATION extracellular
basic FUNCTION
  • acting as an inhibitor of the angiotensin-converting enzyme
  • playing an important role in determination of the surface properties of the casein micelles
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    text calcium ion transport
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
    calcium Ca2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS