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FLASH GENE
Symbol CRIPT contributors: npt/mct - updated : 21/11/2008
HGNC name cysteine-rich PDZ-binding protein
HGNC id 14312
Location 2p21      Physical location : 46.844.324 - 46.852.880
Synonym name
  • postsynaptic protein CRIPT
  • cysteine-rich interactor of PDZ3
  • Synonym symbol(s) HSCP139
    DNA
    TYPE functioning gene
    STRUCTURE 7.88 kb     5 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    5 - 1918 11 101 - Fukunaga (2005)
    EXPRESSION
    Type widely
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestivesalivary gland   highly
    Urinarybladder   highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / hematopoieticbone marrow  highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • ubiquitin activating enzyme signature
  • HOMOLOGY
    Homologene
    FAMILY
  • CRIPT family
  • related PDZ domain-containing membrane-associated guanylate kinase homologues family
  • CATEGORY signaling neurotransmitter
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION microtubule-associated protein enhancing the affinity of DLG4 for calmodulin
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein interacts strongly with the PDZ3 domain of members of the DLG4 family
    cell & other associated with the microtubules
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS