Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | CR1 | contributors: mct - updated : 28-05-2014 |
HGNC name | complement component (3b/4b) receptor 1, including Knops blood group system |
HGNC id | 2334 |
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Corresponding disease |
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Location | 1q32.1 Physical location : 207.669.472 - 207.815.109 | ||
Synonym name | |||
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Synonym symbol(s) | C3BR, CD35, KN, C4BR | ||
EC.number | 2.7.1.- |
DNA |
TYPE | functioning gene |
STRUCTURE | 145.64 kb 39 Exon(s) |
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Genomic sequence alignment details |
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10 Kb 5' upstream gene genomic sequence study |
MAPPING | cloned | Y | linked | Y | status | confirmed |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type |
expressed in | (based on citations) | ||||||||||||||||||||
organ(s) |
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cells |
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cell lineage | hematopoietic cells |
cell lines
fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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conjugated | GlycoP |
mono polymer | monomer |
isoforms | Precursor |
HOMOLOGY |
interspecies | homolog to dog loc609328 |
Homologene |
FAMILY | complement receptor family |
CATEGORY | regulatory , antigen , receptor |
SUBCELLULAR LOCALIZATION | extracellular |
| plasma membrane |
| intracellular |
intracellular,cytoplasm,cytosolic,vesicle |
basic FUNCTION | |
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particles from the circulation, influences interindividual variation in erythrocyte sedimentation rate (ESR) ![]() | |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS | immunity/defense |
PATHWAY |
metabolism |
signaling | signal transduction |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein | |
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cell & other |
REGULATION |
activated by | RUNX1 |
ASSOCIATED DISORDERS |
corresponding disease(s) | KPN |
related resource | Blood Group Antigen Mutation Database |
Other morbid association(s) |
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Susceptibility |
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Variant & Polymorphism other | ![]() |
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |
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