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FLASH GENE
Symbol CPSF3L contributors: - updated : 28-11-2005
Location 1p36.33      Physical location : 1.246.964 - 1.260.046
Genatlas name cleavage and polyadenylation specific factor 3-like
Synonym name integrator complex subunit 11
Synonym symbol(s) RC68
DNA
TYPE functioning gene
STRUCTURE 13.00 kb     0 Exon(s)
MAPPING cloned Y linked N status
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 2122 - 600 - Baillat
isoform 1
- - 1984 - 278 - Baillat
isoform 2
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a putative catalytic beta-lactamase domain
HOMOLOGY
Homologene
FAMILY
CATEGORY unknown/unspecified
SUBCELLULAR LOCALIZATION
basic FUNCTION
  • is recruited to the U1 and U2 snRNA genes and mediates the snRNA's 3' end processing
  • the integrator complex mediates RNA polymerase-II-dependent transcription
  • CELLULAR PROCESS nucleotide, transcription
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component catalytic subunit of the integrator complex of the RNA polymerase II complex
    INTERACTION
    DNA
    RNA
    small molecule
    protein stably associated with RNAPII
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS