Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | CPSF1 | contributors: mct - updated : 23-03-2020 |
HGNC name | cleavage and polyadenylation specific factor 1, 160kDa |
HGNC id | 2324 |
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Corresponding disease |
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Location | 8q24.3 Physical location : 145.618.446 - 145.634.733 | ||
Synonym name | |||
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Synonym symbol(s) | CPSF160, HSU37012, P/cl.18 | ||
EC.number | 2.6.1.2/2.4.2.30 |
DNA |
TYPE | functioning gene |
STRUCTURE | 16.17 kb 38 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | ubiquitous |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||
organ(s) |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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mono polymer | heteromer , tetramer , complex |
HOMOLOGY |
interspecies | ortholog to Drosophila p160 |
Homologene |
FAMILY |
CATEGORY | RNA associated |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,nucleus,nucleoplasm |
CELLULAR PROCESS | nucleotide, transcription, maturation |
PHYSIOLOGICAL PROCESS |
text | polyadenylation |
PATHWAY |
metabolism |
signaling |
INTERACTION |
DNA |
RNA | binding to the AAUAA motif of the pre mRNA,upstream the cleavage site |
small molecule |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | MYP27 |
Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |