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FLASH GENE
Symbol CPNE9 contributors: mct/npt - updated : 30-11-2009
HGNC name copine family member IX
HGNC id 24336
Location 3p25.3      Physical location : 9.745.509 - 9.771.591
Synonym name
  • copine-like protein
  • copine-9
    • Synonym symbol(s) KIAA4217
    DNA
    TYPE functioning gene
    STRUCTURE 26.08 kb     20 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    20 - 2066 61.73 553 - Creutz (1998)
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Endocrineneuroendocrinepituitary   
    Lymphoid/Immunespleen   predominantly
    Nervousnerve   highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a Ca(2+) and phospholipid-binding domain consisting of two C2 domains
  • a core domain in the C-terminal portion that is homologous to the A domain found in certain integrins (Tomsig 2000)
    • conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY
  • copine family
    • CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • exhibits Ca(2+) self-association to form higher-order multimers, and Ca(2+)-dependent, phospholipid binding activity with preference for negatively charged phospholipids over neutral phospholipids (Tomsig 2000)
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS