Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol CPNE5 contributors: npt/ - updated : 27-09-2006
HGNC name copine V
HGNC id 2318
Location 6p21.2      Physical location : 36.708.554 - 36.807.220
Synonym symbol(s) CPN5, COPN5, KIAA1599, DKFZp666C234,
DNA
TYPE functioning gene
STRUCTURE 98.66 kb     21 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
text multiple alternatively spliced transcript variants
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
21 - 3339 65.6 593 - -
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
Digestiveliver   moderately
Endocrinepancreas   moderately
Lymphoid/Immunespleen   predominantly
Nervousbrain   predominantly
 spinal cord   highly
Reproductivefemale systemovary  highly
 male systemtestis  highly
Respiratorylung   moderately
Urinarykidney   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal
Text liver (moderately), brain (predominantly)
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two Ca(2+)- and phospholipid-binding domains known as 'C2 domains'
  • a C terminal region distantly related to the A domain
  • HOMOLOGY
    Homologene
    FAMILY
  • copine family
  • CATEGORY transport
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • calcium-dependent, phospholipid binding protein, potentially involved in regulating membrane trafficking and in protein-protein interactions
  • regulating molecular events at the interface of the cell membrane and cytoplasm
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS cellular trafficking transport
    text vesicular transport, membrane trafficking
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule other,
  • phospholipid
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS