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FLASH GENE
Symbol CPNE2 contributors: - updated : 22-12-2004
HGNC name copine II
HGNC id 2315
Location 16q13      Physical location : 57.126.509 - 57.181.876
Synonym symbol(s) CPN2, COPN2
DNA
TYPE functioning gene
STRUCTURE 55.00 kb     16 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain    
Reproductivemale systemprostate   
Respiratorylung    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two Ca(2+)- and phospholipid-binding domains known as 'C2 domains'
  • and a C terminal region distantly to the A domain,one WWFA domain
  • HOMOLOGY
    Homologene
    FAMILY copine family
    CATEGORY transport
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic,vesicle
    text secretory vesicle
    basic FUNCTION
  • calcium-dependent,phospholipid binding protein,potentially involved in regulating membrane trafficking and in protein-protein interactions
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS cellular trafficking transport
    text
  • vesicular transport
  • membrane trafficking
  • PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    phospholipid binding
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS