Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol CPN2 contributors: npt/ - updated : 07-10-2006
HGNC name carboxypeptidase N, polypeptide 2
HGNC id 2313
Location 3q29      Physical location : 194.060.494 - 194.072.057
Synonym name
  • carboxypeptidase N, polypeptide 2, 83kD
  • carboxypeptidase N regulatory subunit
  • arginine carboxypeptidase (carboxypeptidase N)
  • Synonym symbol(s) ACBP
    EC.number 3.4.17.13
    DNA
    TYPE functioning gene
    STRUCTURE 11.16 kb     2 Exon(s)
    text structure intronless
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    2 - 3028 60.5 545 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveliver    
    cell lineage
    cell lines
    fluid/secretion plasma
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • seven potential N linked glycosylation sites
  • a threonine/serine region which is a potential site for attachment of O linked carbohydrate
  • twelve leucine rich repeats
  • five leucine zipper domains
  • conjugated MetalloP
    mono polymer heteromer , tetramer
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION
  • carboxypeptidase N2 cleaving peptides such as kinins andanaphytaloxins regulatory subunit
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS immunity/defense
    text protecting from potent vasoactive and inflammatory peptides
    PATHWAY
    metabolism
    signaling
    a component
  • heterotetramer (280kDa) with two CPN1 and two CPN2 subunit
  • INTERACTION
    DNA
    RNA
    small molecule metal binding,
    zinc Zn2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS