Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | COX10 | contributors: shn - updated : 15-10-2010 |
HGNC name | COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast) |
HGNC id | 2260 |
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Corresponding disease |
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Location | 17p12 Physical location : 13.972.718 - 14.111.992 | ||
Synonym name | |||
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EC.number | 1.9.3.1, 2.5.1.- |
DNA |
TYPE | functioning gene |
STRUCTURE | 139.28 kb 7 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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regulatory sequence | Binding site |
text structure | lacks conventional TATA and CAAT boxes, but has several potential transcription factor-binding sites |
MAPPING | cloned | Y | linked | N | status | confirmed |
Map | pter - D17S799 - D17S936 - COX10 - D17S921 - D17S955 - cen |
RNA |
TRANSCRIPTS | type | messenger |
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text | transcribed from a sequence tightly linked and distal to CMT1AREPT and from sequences overlapping CMT1AREPT and CMT1AREPC |
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EXPRESSION |
Type | widely |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cells |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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mono polymer | homomer , complex |
HOMOLOGY |
interspecies | ortholog to COX10, S.cerevisiae |
ortholog to COX10, Pan troglodytes | |
ortholog to Cox10, Mus musculus | |
ortholog to cox10, Danio rerio |
Homologene |
FAMILY |
CATEGORY | enzyme , transport |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,organelle,mitochondria,inner | |
intracellular,cytoplasm,organelle,membrane | |
text | localized in mitochondrial inner membrane |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS | mitochondrial transport , electron transport |
text | cellular respiration |
PATHWAY |
metabolism | energetic |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | COX10D |
Other morbid association(s) |
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Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |