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FLASH GENE
Symbol COPG2 contributors: npt/ - updated : 10-07-2002
HGNC name coatomer protein complex, subunit gamma 2
HGNC id 2237
Corresponding disease
SRS7 Silver-Russell syndrome
Location 7q32      Physical location : 130.146.079 - 130.353.598
Synonym name
  • coat protein, non clathrin, gamma 2 COP
  • gamma-2-coat protein
  • Synonym symbol(s) 2-COP, FLJ11781, DKFZp761N09121
    DNA
    TYPE functioning gene
    SPECIAL FEATURE opposite orientation
    text exon 21-24 overlapping the 3'utr of MEST
    STRUCTURE 70.82 kb     34 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked   status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    34 - 3143 97.5 871 - -
    EXPRESSION
    Type ubiquitous
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period pregnancy
    IMPRINTING maternally
    text expressed from the paternal allele in most fetal tissues (maternally imprinted), from both alleles in fetal brain, liver and adult peripheral blood lymphocytes
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    mono polymer polymer
    HOMOLOGY
    interspecies homolog to murine Copg2
    Homologene
    FAMILY
  • COPG family
  • CATEGORY regulatory , transport carrier
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,Golgi
    intracellular,cytoplasm,cytosolic
    basic FUNCTION
  • Golgi coatomer complex, required for budding from golgi membrane
  • component of the coat of non clathrin coated vesicles
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • COPG2/COPZ2
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • binding CDC42
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) SRS7
    Susceptibility
    Variant & Polymorphism
    Candidate gene for SRS
    Marker
    Therapy target
    ANIMAL & CELL MODELS