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FLASH GENE
Symbol COPE contributors: mct/npt - updated : 08/11/2008
HGNC name coatomer protein complex, subunit epsilon
HGNC id 2234
Location 19p13.1      Physical location : 19.010.323 - 19.030.199
Synonym name
  • epsilon-COP
  • coatomer subunit epsilon
  • Synonym symbol(s) FLJ13241, epsilon-COP
    DNA
    TYPE functioning gene
    STRUCTURE 19.88 kb     10 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Map see MYO9B
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    10 - 1134 34 308 - Maruyama (2008)
    9 - 981 - 257 - Maruyama (2008)
    9 - 978 - 256 - Maruyama (2008)
    EXPRESSION
    Type ubiquitous
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestivesalivary gland   highly
    Lymphoid/Immunethymus   highly
    Reproductivefemale systemovary  highly
    Skin/Tegumentskin   highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
  • COPE family
  • CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,Golgi
    intracellular,cytoplasm,cytosolic,vesicle
    basic FUNCTION
  • Golgi coatomer complex
  • component of the coat of non clathrin coated vesicles, involved in the transport between endoplasmic reticulum and Golgi
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacts with RCHY1 that ubiquitylates COPE (interaction between RCHY1 and epsilon-COP is affected by the presence of androgen)
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS