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FLASH GENE
Symbol COMMD8 contributors: - updated : 14-02-2007
HGNC name COMM domain containing 8
HGNC id 26036
Location 4p12      Physical location : 47.452.814 - 47.465.676
Synonym symbol(s) FLJ20502
DNA
TYPE functioning gene
STRUCTURE 12.00 kb     5 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrineparathyroid   highly
Skin/Tegumentskin    
Urinarybladder   highly
 kidney   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / hematopoieticbone marrow  highly
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • COMM (copper metabolism gene MURR1) domain
  • HOMOLOGY
    interspecies homolog to rattus LOC289603
    homolog to murine Commd8
    Homologene
    FAMILY MURR1/COMMD1 family
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION suppressing NF-kappaB not by affecting nuclear translocation or binding of NF-kappaB to cognate motifs
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS