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FLASH GENE
Symbol COMMD2 contributors: - updated : 14-02-2007
HGNC name COMM domain containing protein 2
HGNC id 24993
Location 3q25.1      Physical location : 149.456.256 - 149.470.286
Synonym symbol(s) HSPC042, MGC57611
DNA
TYPE functioning gene
STRUCTURE 11.00 kb     5 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivepharynx   highly
 salivary gland   highly
Respiratoryrespiratory tracttrachea  highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / hematopoieticbone marrow  highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • COMM (copper metabolism gene MURR1) domain
  • HOMOLOGY
    Homologene
    FAMILY MURR1/COMMD1 family
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION suppressing NF-kappaB not by affecting nuclear translocation or binding of NF-kappaB to cognate motifs
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS