basic FUNCTION
| involved in supramolecular organization of fibril bundles |
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may have a functional role in maintaining cell differentiation (Ruehl 2005) |
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may have a tissue-specific role in the structure-function relationship of connective tissues (Ansorge 2009) |
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with COL12A1, might well be able to serve different functions during human embryonic development although their structures are highly similar (Thierry 2004) |
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may be involved in basement membrane regulation providing specific molecular bridges between fibrils and other matrix components (Thierry 2004) |
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fibril-associated collagen with an interrupted triple helix, interacting with the fibril surface and implicated as a regulator of fibrillogenes (Ansorge 2009) |
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fibril-associated collagen with an interrupted triple helix (FACIT), regulating early stages of fibrillogenesis in connective tissues of high mechanical demand |
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role in the formation of the cardiac interstitium during embryonic development, suggesting the importance of the collagen network for myocardial cell survival, and function of the working myocardium after birth |