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FLASH GENE

Symbol

CNTNAP4

contributors: mct - updated : 17-08-2011

HGNC name	contactin associated protein-like 4
HGNC id	18747

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	16q23.1      Physical location : 76.311.175 - 76.593.135
Synonym name	cell recognition protein CASPR4
Synonym symbol(s)	CASPR4, KIAA1763

DNA

TYPE	functioning gene

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed CNTNAP4 I1 - - 4455 - 1311 - Spiegel CNTNAP4 I2 - - 2339 - 721 - Spiegel

EXPRESSION

Type	restricted

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Nervous brain diencephalon hypothalamus       brain limbic system hippocampus       brain midbrain substantia nigra       nerve cranial nerve olfactory nerve     Olfactory (smell) olfactory bulb

cells

System Cell Pubmed Species Stage Rna symbol nervous cerebellum

cell lineage

cell lines

fluid/secretion

at STAGE

physiological period

fetal

Text

brain

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	two epidermal growth factor repeats and fourlaminin G domains,
	an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains,
	and thrombospondin N-terminal-like domains.

HOMOLOGY

Homologene

FAMILY

neurexin family

CATEGORY

adhesion , regulatory

SUBCELLULAR LOCALIZATION	plasma membrane
	intracellular
	intracellular,cytoplasm,organelle,membrane
	intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth

basic FUNCTION

playing a potential role in cell recognition within the nervous system

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein	interacted with PDZ domain-containing proteins of CASK
	SDC1 and CASPR4, are potential TIAM1 PDZ domain binding proteins

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS