basic FUNCTION
| negative control of cell proliferation associated with cell-cell contact through interaction with BTG1 |
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regulates cell growth in a manner dependent on its deadenylase activity |
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may be involved in various cellular events that include cell proliferation |
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play a role in cell survival, in contrast to the CNOT7 and CNOT8 deadenylase subunits of CCR4-NOT complex |
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key regulator of insulin-like growth factor-binding protein 5, which mediates cell cycle arrest and senescence via a TP53-dependent pathway |
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CNOT7/8 catalytic subunits are essential for deadenylation, which is necessary to maintain cell viability, whereas CNOT6/6L are not |