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FLASH GENE
Symbol CNNM1 contributors: mct/npt - updated : 28-12-2016
HGNC name cyclin M1
HGNC id 102
Location 10q24.2      Physical location : 101.088.855 - 101.154.085
Synonym name ancient conserved domain protein 1
Synonym symbol(s) ACDP1, FLJ31632
DNA
TYPE functioning gene
STRUCTURE 67.56 kb     11 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
11 initiation site 5988 - 951 - Wang (2003)
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain    
 nervecranial nerveoptic nerve  
Reproductivemale systemtestis   
Visualeyeuveachoroid  
 eyeretinafovea  
 eyeretinamacula  
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelial    
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal
Text eye, RPE, choroid, lens, retina, eye anterior segment
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • 31-amino acid sequence motif that is present in the cyclin box
  • a cyclic nucleotide-monophosphate (cNMP)-binding domain
  • two CBS forming a stable globular domain
  • HOMOLOGY
    interspecies homolog to murine Cnnm1
    Homologene
    FAMILY
  • ACDP family
  • CATEGORY regulatory , transport carrier
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • implicated in divalent ion transport (Tang 2010)
  • CELLULAR PROCESS cell cycle, division, mitosis
    cell life, proliferation/growth
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS