basic FUNCTION
| part of conserved protein family that acts in the selective transport and maturation of TGFalpha family proteins |
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acting as chaperones for other proteins |
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can affect the trafficking of AMPARS (GRIA1, GRIA2, GRIA3, and GRIN2B), they were not detected on the surface of neurons and failed to alter the kinetics of endogenous AMPARs |
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can modestly enhance the surface expression of AMPARs in neurons, in the absence of CACNG2 |
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modulates neuronal AMPA receptor auxiliary subunit assembly by regulating the number of TARPs within an AMPA receptor complex to modulate receptor gating and pharmacology |