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FLASH GENE
Symbol CMBL contributors: KTN/npt - updated : 12/11/2008
HGNC name carboxymethylenebutenolidase homolog (Pseudomonas)
HGNC id 25090
Location 5p15.2      Physical location : 10.277.707 - 10.308.168
Synonym name carboxymethylenebutenolidase-like (Pseudomonas)
Synonym symbol(s) FLJ23617
EC.number 3.1.1.45
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
text part of the clc gene cluster
STRUCTURE 30.46 kb     6 Exon(s)
MAPPING cloned Y linked N status confirmed
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
6 - 4047 27.9 245 - Ewing (2007)
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrineneuroendocrinepituitary  highly
Reproductivefemale systemuteruscervix moderately
Urinarykidney   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connective   predominantly
Muscular   moderately
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated Other
HOMOLOGY
interspecies homolog to rattus Cmbl (84.5 pc)
homolog to murine Cmbl (82.9 pc)
Homologene
FAMILY
  • dienelactone hydrolase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • catalyzing the conversion of dienelactones to maleylacetate
  • involved in the utilization of chlorocatechol
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    Other acetylated
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS