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FLASH GENE
Symbol CLUH contributors: mct - updated : 18-04-2017
HGNC name clustered mitochondria homolog
HGNC id 29094
Location 17p13.3      Physical location : -
Genatlas name Clu1/CluA homologue
Synonym name
  • cDNA sequence,expressed in brain,>100kDa,related to D Disco
  • deum 150 kDa
  • hypothetical protein LOC23277
  • KIAA0664
  • Synonym symbol(s) CLU1, DKFZp686L05242, DKFZp686M09233, FLJ23672, eIF-3, KIAA0664
    DNA
    TYPE functioning gene
    STRUCTURE 22.25 kb     26 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    26 - 5252 146.5 1309 - 2014 25349259
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrain    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    HOMOLOGY
    intraspecies homolog to D Disco´deum 150 kDa protein CLUA
    Homologene
    FAMILY
  • eIF-3 p135 family
  • CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    basic FUNCTION
  • is a cytosolic messenger ribonucleic acid (RNA; mRNA)-binding protein
  • regulates mitochondrial biogenesis by binding mRNAs of nuclear-encoded mitochondrial proteins
  • CLUH plays likely a role in the subnuclear transport of progeny viral ribonucleoprotein (vRNP)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • CLUH specifically binds a subset of mRNAs encoding mitochondrial proteins
  • cell & other
    REGULATION
    Other is coregulated both with genes encoding mitochondrial proteins and with genes involved in ribosomal biogenesis and translation
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS