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FLASH GENE
Symbol CLPS contributors: npt/ - updated : 27-02-2008
HGNC name colipase, pancreatic
HGNC id 2085
Location 6p21.31      Physical location : 35.762.759 - 35.765.102
Synonym name pancreatic colipase preproprotein
EC.number 3.1.1.3
DNA
TYPE functioning gene
STRUCTURE 2.34 kb     3 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
3 - 539 - 112 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrinepancreas    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
isoforms Precursor
HOMOLOGY
Homologene
FAMILY
  • colipase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • non covalently anchoring lipase to the surface of lipid miscelles
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism lipid/lipoprotein
    signaling
    a component
  • stoichiometric complex with lipase
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • binding to the C terminal,non catalytic domain of lipase, therely stabilizing an active conformation and considerably increasing the hydrophobic binding site
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS