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FLASH GENE
Symbol CLEC1A contributors: mct - updated : 31-03-2008
HGNC name C-type lectin domain family 1, member A
HGNC id 24355
Location 12p13.31      Physical location : 10.223.081 - 10.251.605
Synonym name C-type lectin-like receptor-1
Synonym symbol(s) MGC34328, CLEC1, CLECSF1R
DNA
TYPE functioning gene
STRUCTURE 28.00 kb     6 Exon(s)
MAPPING cloned Y linked N status provisional
regionally located located near the natural killer cell gene complex
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
6 - 1791 - 280 - Ebner (2003)
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveesophagus   highly
Endocrineneuroendocrinepituitary  highly
Hearing/Equilibriumear   highly
Nervousgangliasensory gangliadorsal root  
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a single carbohydrate recognition domain (CRD) with 6 conserved and 2 additional cysteine residues
  • a cytoplasmic putative immunoreceptor tyrosine-based motif (YSST) and several potential phosphorylation sites
    • HOMOLOGY
    Homologene
    FAMILY C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily.
    CATEGORY adhesion , signaling
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm
    intracellular,nuclear envelope
    basic FUNCTION playing a role in regulating dendritic cell function
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS