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FLASH GENE

Symbol

CLEC10A

contributors: - updated : 02-05-2006

HGNC name	C-type lectin domain family 10, member A
HGNC id	16916

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	17p13.1      Physical location : 6.977.856 - 6.983.600
Synonym name	macrophage C-type lectin
	C-type (calcium dependent, carbohydrate-recognition domain)lectin, superfamily member 13 /14 (macrophage derived)
Synonym symbol(s)	HML, HML2, CLECSF13, CLECSF14, CD301

DNA

TYPE	functioning gene
STRUCTURE	5.00 kb     10 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed variant 1 - - 1788 35.3 316 - Suzuki nine exons variant 2 - splicing 1716 32.7 292 - Suzuyi a distinct sixth exon compared to variant 1

EXPRESSION

Type

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Reproductive female system breast mammary gland     Respiratory lung

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Connective bone subchondral

cells

System Cell Pubmed Species Stage Rna symbol Blood/Hematopoietic leukocyte Digestive parenchymal Lymphoid/Immune macrophage

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

a calcium dependent, carbohydrate-recognition domain (or C-type lectin domain)

HOMOLOGY

Homologene

FAMILY

C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily

CATEGORY

immunity/defense , antigen

SUBCELLULAR LOCALIZATION	plasma membrane
text	integral membrane protein type 2

basic FUNCTION

may function as a cell surface antigen

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

immunity/defense

text	immune response

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule	other,
	sugar binding

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS