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FLASH GENE
Symbol CLDN23 contributors: npt/ - updated : 21-01-2005
HGNC name claudin 23
HGNC id 17591
Location 8p23.1      Physical location : 8.559.665 - 8.561.616
Synonym symbol(s) CLDNL, 2310014B08Rik, hCG1646163
DNA
TYPE functioning gene
STRUCTURE 1.95 kb     1 Exon(s)
MAPPING cloned Y linked N status provisional
Physical map
LOC392184 8 similar to chromosome 11 open reading frame2; chromosome  11 open reading frame2 LOC389616 8 similar to seven transmembrane helix receptor LOC389617 8 similar to hypothetical protein FLJ10408 LOC389618 8 similar to FLJ10408 protein LOC389619 8 similar to FLJ10408 protein LOC392185 8 similar to 60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa chaperonin) (CPN60) (Heat shock protein 60) (HSP-60) (Mitochondrial matrix protein P1) (P60 lymphocyte protein) (HuCHA60) DEFB4 8p23.1-p22 defensin, beta 4 LOC392186 8 similar to hypothetical protein LOC169270 LOC392187 8 similar to ubiquitin-specific protease 17-like protein LOC392188 8 similar to ubiquitin-specific protease 17-like protein LOC392189 8 similar to ubiquitin-specific protease 17-like protein LOC389620 8 similar to hypothetical protein FLJ10408 LOC340407 8p23.1 similar to FLJ10408 protein LOC389621 8 similar to seven transmembrane helix receptor LOC392190 8 similar to chromosome 11 open reading frame2; chromosome  11 open reading frame2 LOC389622 8 hypothetical gene supported by AK124896; BC037255; BC038200 LOC286042 8p23.1 similar to Alkaline sphingomyelinase LOC392191 8 similar to mannosyltransferase DKFZp761P0423 8p23.1 hypothetical protein DKFZp761P0423 CLDN23 8p23.1 claudin 23 MFHAS1 8p23.1 malignant fibrous histiocytoma amplified sequence 1 MRPS18CP2 8p23.1 mitochondrial ribosomal protein S18C pseudogene LOC392192 8 similar to 60S ribosomal protein L10 (QM protein homolog) RNU7P4 8p23.1 RNA, U7 small nuclear pseudogene 4 PPP1R3B 8p23.1 protein phosphatase 1, regulatory (inhibitor) subunit 3B TNKS 8p11 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
1 - 1972 31.7 292 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinelarge intestinecolon  
 stomach    
Reproductivefemale systemplacenta   
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectivebonesubchondral  
cells
SystemCellPubmedSpeciesStageRna symbol
Lymphoid/ImmuneB cell
cell lineage germinal center B cell
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
  • claudin family
  • CATEGORY adhesion , structural protein
    SUBCELLULAR LOCALIZATION     plasma membrane,junction,tight
        intracellular
    intracellular,nucleus
    basic FUNCTION
  • tight junction specific obliteration of the intercellular space
  • candidate tumor suppressor gene implicated in intestinal-type gastric cancer
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene candidate tumor suppressor gene implicated in intestinal-type gastric cancer
    Marker
    Therapy target
    ANIMAL & CELL MODELS