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FLASH GENE
Symbol CITED4 contributors: npt/ - updated : 05-01-2006
HGNC name Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
HGNC id 18696
Location 1p34.1      Physical location : 41.326.728 - 41.328.018
Synonym name
  • transcriptional co-activator 4
  • MSG1-related protein 2
  • Synonym symbol(s) MRG-2 , MRG2
    DNA
    TYPE functioning gene
    STRUCTURE 1.29 kb     1 Exon(s)
    Genomic sequence alignment details
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    1 - 1312 18 184 - -
    EXPRESSION
    Type ubiquitous
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart   highly
    Digestiveliver    
    Endocrinepancreas    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatumskeletal  
    cell lineage
    cell lines breast and bladder cancer
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • Glu/Asp-rich carboxy-terminal domain p300/CBP binding motif
  • HOMOLOGY
    interspecies ortholog to murine Cited4
    homolog to rattus Cited4
    Homologene
    FAMILY
  • transcriptional coactivators family
  • CITED family
  • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    basic FUNCTION
  • regulating transcription by binding CREB-binding protein and p300
  • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • binding to EP300, CREBBP, TFAP2
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS