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FLASH GENE
Symbol CHST7 contributors: - updated : 11-03-2006
HGNC name carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
HGNC id 13817
Location Xp11.23      Physical location : 46.433.191 - 46.457.837
Synonym name chondroitin 6-sulfotransferase-2
Synonym symbol(s) C6ST2, C6ST-2
EC.number 2.8.2.5
DNA
TYPE functioning gene
STRUCTURE 24.00 kb     2 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
LOC347333 Xp11.3 similar to tau tubulin kinase 2; tau-tubulin kinase LOC392452 X similar to RIKEN cDNA 5230400G24 LOC392453 X similar to arginine/serine-rich splicing factor 6; splicing factor, arginine/serine-rich, 55 kDa; pre-mRNA splicing factor SRP55 LOC139060 Xp11.3 similar to Keratin, type I cytoskeletal 18 (Cytokeratin 18) (K18) (CK 18) LOC392454 X similar to Proliferating cell nuclear antigen (PCNA) (Cyclin) PCNAP Xp11 proliferating cell nuclear antigen pseudogene LOC392455 X similar to beta actin LOC392456 X similar to beta catenin-like 1; nuclear associated protein; chromosome 20 open reading frame 33 LOC389849 X similar to Glyceraldehyde 3-phosphate dehydrogenase, liver (GAPDH) FLJ20344 Xp11.3 hypothetical protein FLJ20344 RNU6P1 Xp11.3 RNA, U6 small nuclear pseudogene 1 LOC392457 X similar to Antigen KI-67 CHST7 Xp11.23 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 SLC9A7 Xp11.4-p11.1 solute carrier family 9 (sodium/hydrogen exchanger), isoform 7 RP2 Xp11.23 retinitis pigmentosa 2 (X-linked recessive) PHF16 Xp11.3-p11.23 PHD finger protein 16 RGN Xp11.3-q11.2 regucalcin (senescence marker protein-30) RNU12 Xp11.3 RNA, U12 small nuclear P17.3 Xp11.3 neuronal protein 17.3 RBM10 Xp11.23 RNA binding motif protein 10 UBE1 Xp11.23 ubiquitin-activating enzyme E1 (A1S9T and BN75 temperature sensitivity complementing) INE1 Xp11.4-p11.3 inactivation escape 1 PCTK1 Xp11.3 PCTAIRE protein kinase 1 USP11 Xp21.2-p11.2 ubiquitin specific protease 11 ZNF157 Xp11.23 zinc finger protein 157 (HZF22) ZNF41 Xp11.23 zinc finger protein 41 LOC389850 X similar to hypothetical protein, MGC:7199 TIMP1 Xp11.23 tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor) ARAF1 Xp11.3-p11.23 v-raf murine sarcoma 3611 viral oncogene homolog 1 SYN1 Xp11.23 synapsin I
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticspleen    
 thymus    
Digestiveintestinesmall intestine   
Endocrinepancreas    
Nervousbrain    
Reproductivefemale systemovary   
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Lymphoid    
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period embryo, fetal
Text developmentaly regulated
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to murine Chst7
homolog to Drosophila CG3701
homolog to C.elegans C01G12.8
Homologene
FAMILY sulfotransferase gene family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,membrane
intracellular,cytoplasm,organelle,Golgi
basic FUNCTION
  • sulfation of polymer chondroitin
  • transfering sulfate to N-acetylgalactosamine
  • playing a role in neural cellular adhesion, migration, neurite outgrowth and axonal regeneration
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS development
    PATHWAY
    metabolism carbohydrate
    signaling
    polysaccharides
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS