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FLASH GENE
Symbol CHST7 contributors: - updated : 11-03-2006
HGNC name carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
HGNC id 13817
Location Xp11.23      Physical location : 46.433.191 - 46.457.837
Synonym name chondroitin 6-sulfotransferase-2
Synonym symbol(s) C6ST2, C6ST-2
EC.number 2.8.2.5
DNA
TYPE functioning gene
STRUCTURE 24.00 kb     2 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticspleen    
 thymus    
Digestiveintestinesmall intestine   
Endocrinepancreas    
Nervousbrain    
Reproductivefemale systemovary   
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Lymphoid    
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period embryo, fetal
Text developmentaly regulated
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to murine Chst7
homolog to Drosophila CG3701
homolog to C.elegans C01G12.8
Homologene
FAMILY sulfotransferase gene family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,membrane
intracellular,cytoplasm,organelle,Golgi
basic FUNCTION
  • sulfation of polymer chondroitin
  • transfering sulfate to N-acetylgalactosamine
  • playing a role in neural cellular adhesion, migration, neurite outgrowth and axonal regeneration
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS development
    PATHWAY
    metabolism carbohydrate
    signaling
    polysaccharides
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS