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FLASH GENE
Symbol CHID1 contributors: KTN/npt - updated : 22-01-2009
HGNC name chitinase domain containing 1
HGNC id 28474
Location 11p15.5      Physical location : 867.859 - 915.058
Synonym name stabilin-1-interacting chitinase-like protein
Synonym symbol(s) SI-CLP, GL008, PSEC0104, SB139, MGC3234, FLJ42707
DNA
TYPE functioning gene
STRUCTURE 42.43 kb     13 Exon(s)
MAPPING cloned Y linked N status confirmed
Map pter - CHID1 - D11S1363 - D11S4177 - cen
Authors UCSC (2009)
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 3558 44.8 393 - -
  • encoding the same protein than variants 2 and 3
  • - - 3448 44.8 393 - -
  • differing in the 5' UTR compared to variant 1
  • encoding the same protein than variants 1 and 3
  • 13 - 3344 44.8 393 - -
  • differing in the 5' UTR compared to variant 1
  • encoding the same protein than variants 1 and 2
  • - - 3419 47.5 418 - -
  • differing in the 5' UTR compared to variant 1
  • containing an alternate in-frame exon in the 5' coding region compared to variant 1
  • - - 3252 41.5 362 - -
  • differing in the 5' UTR compared to variant 1
  • lacking an alternate in-frame exon in the central coding region compared to variant 1
  • EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Lymphoid/Immunemacrophage
    cell lineage cells of monocytic, T, B and epithelial origin (Kzhyshkowska 2006)
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies homolog to rattus Chid1 (89.3 pc)
    homolog to murine Chid1 (87.9 pc)
    Homologene
    FAMILY
  • glycosyl hydrolase 18 family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION extracellular
        intracellular
    intracellular,cytoplasm,organelle,lysosome
    basic FUNCTION
  • acting as a chitinase
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism carbohydrate
    signaling
    chitin catabolic process
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacting with STAB1 (Kzhyshkowska 2006)
  • cell & other
    REGULATION
    induced by interleukin-4 and dexamethasone in the macrophages (Kzhyshkowska 2006)
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS