SUBCELLULAR LOCALIZATION
| intracellular
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| intracellular,cytoplasm,organelle,mitochondria,interspace
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| intracellular,cytoplasm,cytosolic
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| intracellular,cytoplasm,cytoskeleton,microtubule,centrosome
|
| intracellular,cytoplasm,cytoskeleton,microtubule,mitotic spindle
|
text
| present both in the cytosol and in the mitochondrial intermembrane space |
basic FUNCTION
| distal appendages component essential for ciliogenesis |
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plays a role in non-associative jump-reflex habituation |
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plays a role in the late assembly steps of complex IV |
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role for CEP89 in mitochondrial metabolism |
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required for mitochondrial integrity, membrane depolarization and synaptic transmission of photoreceptor neurons, and for (sub)synaptic organization of the larval neuromuscular junction |
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play an important role in mitochondrial metabolism, especially complex IV activity, and are required for neuronal and cognitive function across evolution |