basic FUNCTION
| key protein essential for maintaining microtubule-organizing activity and structural integrity of the centrosome ) |
|
also involved in gammatubulin ring complexes recruitment to the centrosome |
|
CEP72 is the key protein essential for maintaining microtubule-organizing activity and structural integrity of the centrosome |
|
CEP290 and CEP72 in centriolar satellites regulate the ciliary localization of BBS4, which in turn affects assembly and recruitment of the BBSome |
|
represents a putative oncogene in colorectal cancer that might negatively regulate the mitotic function of BRCA1 to ensure chromosomal stability |