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FLASH GENE
Symbol CEACAM19 contributors: npt - updated : 05-03-2010
HGNC name carcinoembryonic antigen-related cell adhesion molecule 19
HGNC id 31951
Location 19q13.31      Physical location : 45.174.723 - 45.187.625
Synonym name
  • CEA-like gene 1
  • carcinoembryonic antigen-like 1
  • Synonym symbol(s) CEAL1, MGC105097
    DNA
    TYPE functioning gene
    SPECIAL FEATURE component of a cluster
    STRUCTURE 12.90 kb     8 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    8 - 2265 - 299 - -
    8 - 2262 - 300 - -
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestivemouthtongue   
    Endocrinepancreas    
    Urinarybladder    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • two Immunoglobulin-like (Ig-like) transmembrane domains, present in most of the CEA proteins
  • one highly conserved domain of eukaryotic translation initiation factors
  • conjugated GlycoP
    HOMOLOGY
    interspecies ortholog to murine Ceacam19
    Homologene
    FAMILY
  • CEA multigene family
  • immunoglobulin superfamily
  • CATEGORY antigen
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    repressed by dexamethasone in BT-474 breast cancer cell lines
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    in ovarian cancers which are clinically more aggressive
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS