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FLASH GENE
Symbol CDY2A contributors: - updated : 03-03-2006
HGNC name chromodomain protein, Y-linked, 2A
HGNC id 1810
Location Yq11.23      Physical location : 19.990.141 - 20.139.625
Synonym name
  • chromodomain protein, Y chromosome, 2
  • chromodomain protein, Y-linked, 2
  • testis-specific chromodomain protein Y 2
  • Synonym symbol(s) CDY, CDY2
    EC.number 2.3.1.48
    DNA
    TYPE functioning gene
    STRUCTURE 1.00 kb     1 Exon(s)    multiple Copie(s)
    MAPPING cloned Y linked N status provisional
    regionally located in the AZFC deleted region
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Reproductivemale systemtestis  specific
    cell lineage late spermatids
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a chromodomain
  • a histone acetyltransferase catalytic domain
  • a SNF2 related helicase (ATPase) domain
  • HOMOLOGY
    interspecies ortholog to chimpanzee cdy1
    intraspecies paralog to CDY1
    Homologene
    FAMILY CHD family
    CATEGORY enzyme , DNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    text localized to the nucleus of late spermatids where histone hyperacetylation takes place
    basic FUNCTION
  • involved in compaction during spermatogenesisin early stage
  • acting as gene repressor
  • CELLULAR PROCESS cell life, differentiation
    PHYSIOLOGICAL PROCESS reproduction/sex
    text spermatogenesis
    PATHWAY
    metabolism
    signaling
    a component components of heterochromatin-like complexes
    INTERACTION
    DNA binding
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS