Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol CDS1 contributors: mct/npt - updated : 28/10/2008
HGNC name CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
HGNC id 1800
Location 4q21.23      Physical location : 85.504.056 - 85.572.492
Synonym name
  • CDP-DAG synthase 1
  • CDP-DG synthetase 1
  • CDP-diacylglycerol synthase 1
  • CDP-diglyceride pyrophosphorylase 1
  • Synonym symbol(s) CDS
    EC.number 2.7.7.41
    DNA
    TYPE functioning gene
    STRUCTURE 66.29 kb     13 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - - 5000 - - heart and liver Heacock, 96
    - - - 3000 - - heart and pancreas Heacock, 96
    13 - 4546 53.2 461 - Volta (1999)
    EXPRESSION
    Type widely
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart    
    Digestiveintestinesmall intestine   
    Endocrineparathyroid   highly
    Reproductivefemale systemovary   
     male systemtestis   
     male systemprostate   
    Urinarykidney   highly
    Visualeye    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / Hematopoietic    
    Epithelialsecretoryglandularendocrine 
    Epithelialsensoryvisualphotoreceptor layer 
    Muscularstriatumcardiac  
    Nervouscentral   
    Nervousperipherous   
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Blood/Hematopoieticleukocyte
    Nervousneuron
    Visualcone photoreceptor
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period fetal, pregnancy
    Text placenta, fetal kidney, lung, brain and liver
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • three putative membrane-spanning domains
  • HOMOLOGY
    interspecies homolog to C.elegans c33h5.18
    homolog to E.coli cds
    homolog to yeast cds
    homolog to Drosophila cds
    intraspecies homolog to cds2
    homolog to reticulum endothelial
    Homologene
    FAMILY
  • CDS family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    intracellular,nuclear envelope
    basic FUNCTION
  • regulator of cellular phosphatidylinositol content
  • diacylglycerol cholinephosphotransferase (converting phosphatidic acid to CDP-diacylglycerol)
  • playing a role in phototransduction
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism lipid/lipoprotein
    signaling signal transduction , sensory transduction/vision
    phospholipid biosynthesis
    a component
  • involved in phosphoinositide mediated signaling pathway
  • INTERACTION
    DNA
    RNA
    small molecule metal binding, cofactor,
  • Mg2+
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS