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FLASH GENE
Symbol CDO1 contributors: mct - updated : 26-03-2008
HGNC name cysteine dioxygenase, type I
HGNC id 1795
Location 5q22-q23      Physical location : 115.140.431 - 115.152.405
EC.number 1.13.11.20
DNA
TYPE functioning gene
STRUCTURE 11.00 kb     5 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status confirmed
Physical map
STK22D 5q22.2 serine/threonine kinase 22D (spermiogenesis associated) LOC389316 5 LOC389316 FLJ21940 5q22.3 FLJ21940 protein KCNN2 5q22.3 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 TRIM36 5q22 tripartite motif-containing 36 PGGT1B 5q23.1 protein geranylgeranyltransferase type I, beta subunit MGC39633 5q23.1 hypothetical protein MGC39633 CTNNAP1 5q22 catenin (cadherin-associated protein), alpha pseudogene 1 LOC340068 5q23.1 similar to T-complex protein 1, epsilon subunit (TCP-1-epsilon) (CCT-epsilon) FEM1C 5q22-q23.1 fem-1 homolog c (C.elegans) TIRP 5q23.1 TRIF-related adaptor molecule CGI-109 5q23.1 CGI-109 protein CDO1 5q21-q22 cysteine dioxygenase, type I APG12L 5q21-q22 APG12 autophagy 12-like (S. cerevisiae) AP3S1 12p13.2-p13.1 adaptor-related protein complex 3, sigma 1 subunit FLJ90650 5q23.1 hypothetical protein FLJ90650 LOC389317 5 similar to 40S ribosomal protein S25 PTD002 5q23.1 PTD002 protein SEMA6A 5q23 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A RPS17P2 5q23.1 ribosomal protein S17 pseudogene 2
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
5 - 1627 - 200 - Dominy (2007)
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver    
Nervousbrain    
Reproductivefemale systemplacenta  highly
Respiratorylung    
Visualeye   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectiveadipose  highly
cells
SystemCellPubmedSpeciesStageRna symbol
Nervousastrocyte
Respiratoryepithelial cell
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES basic
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,cytosolic
basic FUNCTION
  • initial and rate-limiting enzyme involved in the oxidative degradation of cysteine to inorganic sulphate
  • capable of altering intracellular cysteine levels as well as glutathione levels
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism aminoacid
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS