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FLASH GENE
Symbol CDK20 contributors: np/ - updated : 17/09/2008
HGNC name cyclin-dependent kinase 20
HGNC id 21420
Location 9q22.1      Physical location : 90.581.360 - 90.589.695
Synonym name
  • cell cycle related kinase
  • CAK-kinase p42
  • CDK-activating kinase p42
  • cyclin-dependent protein kinase H
  • cell division protein kinase 20
  • Synonym symbol(s) CDCH, p42, PNQALRE, CCRK
    EC.number 2.7.11.22
    DNA
    TYPE functioning gene
    STRUCTURE 8.31 kb     8 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    7 - 2382 - 338 - Qiu (2008)
    7 - 2343 - 325 - Qiu (2008)
    8 - 2406 - 346 - Qiu (2008)
    - - 2219 - 243 - -
    - - 2315 - 275 - -
    EXPRESSION
    Type restricted
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Lymphoid/Immunethymus    
    Nervousbrain   highly
    Respiratorylung    
    Urinarykidney   highly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
  • protein kinase superfamily
  • CMGC Ser/Thr protein kinase family
  • CDC2/CDKX subfamily
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • having a function in activating CDKs, but instead reinforce the notion of CDK7 as the major, and to date the only, CDK-activating kinase in cells
  • having an indispensable role for cell growth
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS