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FLASH GENE
Symbol CDK16 contributors: np/ - updated : 29-07-2004
HGNC name cyclin-dependent kinase 16
HGNC id 8749
Location Xp11.3      Physical location : 47.077.527 - 47.089.392
Synonym name
  • PCTAIRE protein kinase 1
  • PCTAIRE-motif protein kinase 12
  • serine/threonine-protein kinase
  • cell division protein kinase 16
    • Synonym symbol(s) PCTK1, PCTAIRE, PCTAIRE1, PCTGAIRE, FLJ16665
    EC.number 2.7.11.22
    DNA
    TYPE functioning gene
    SPECIAL FEATURE
    text escaping inactivation in human
    STRUCTURE 11.87 kb     16 Exon(s)
    MAPPING cloned Y linked   status confirmed
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    16 splicing 3169 55.6 496 - PMID: 12154078
    16 splicing 3280 56.2 502 - PMID: 12154078
    - - 3034 63.3 570 - -
    - - 2987 51 448 - -
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrain    
    Reproductivemale systemtestis  highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • serine/threonine protein kinase, PCTAIRE motif
    • HOMOLOGY
    interspecies homolog to cdc2
    Homologene
    FAMILY
  • protein kinase superfamily
  • CMGC Ser/Thr protein kinase family
  • CDC2/CDKX subfamily
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    basic FUNCTION
  • may be playing a role in signal transduction cascades in terminally differentiated cells
    • CELLULAR PROCESS cell cycle
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacting with YWHAH,YWHAZ
  • interacting with CDK5 in muscle
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS