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FLASH GENE
Symbol CDH9 contributors: mct - updated : 15-09-2009
HGNC name cadherin 9, type 2 (T1-cadherin)
HGNC id 1768
Location 5p14.1      Physical location : 26.880.708 - 27.038.689
Synonym name
  • cadherin-9
  • T1-cadherin
  • Synonym symbol(s) MGC125386
    DNA
    TYPE functioning gene
    STRUCTURE 157.98 kb     12 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    LOC266786 5p14 nucleoporin 50 kDa pseudogene SMA4 5q13 SMA4 CDH12 5p14-p13 cadherin 12, type 2 (N-cadherin 2) PMCHL1 5p14 pro-melanin-concentrating hormone-like 1 LOC391771 5 similar to protein tyrosine phosphatase, non-receptor type 11; protein-tyrosine phosphatase 2C; Noonan syndrome 1 LOC389276 5 similar to CDNA sequence BC012016 PRDM9 5p14 PR domain containing 9 FLJ34836 5p14.2 hypothetical protein FLJ34836 LOC389277 5 hypothetical gene supported by NM_022476 CDH10 5p14-p13 cadherin 10, type 2 (T2-cadherin) MSNL1 5p14.2-p14.1 moesin-like 1 LOC391772 5 similar to cyclin B3 isoform 3 CDH9 5p14 cadherin 9, type 2 (T1-cadherin) LOC391773 5 similar to Striatin PGBD3P2 5p13.3 piggyBac transposable element derived 3 pseudogene 2 HPRTP2 5p14-p13.3 hypoxanthine phosphoribosyltransferase pseudogene 2 LOC391774 5 similar to hypothetical protein CDH6 5p15.32-p14.2 cadherin 6, type 2, K-cadherin (fetal kidney) RNASE3L 5p15.1 cadherin 6, type 2, K-cadherin (fetal kidney) FLJ11193 5p13.3 hypothetical protein FLJ11193 PDZK3 5p13.2 PDZ domain containing 3 GOLPH3 5p14.1 golgi phosphoprotein 3 (coat-protein) LOC202122 5p13.3 similar to ribosomal protein L27 PIP3AP 5p15.33 phosphatidylinositol-3-phosphate associated protein ZFR 5p13.2 zinc finger RNA binding protein LOC391775 5 similar to Chromosome 1 open reading frame 37 PC4 5p13.3 activated RNA polymerase II transcription cofactor 4 NPR3 5p14-p13 natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) FLJ14054 5p13.3 hypothetical protein FLJ14054 LOC389278 5 similar to 40S ribosomal protein S8 TARS 5p13.3-p13.2 threonyl-tRNA synthetase
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    12 - 3075 - 789 - 2009 19404256
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrain    
    Urinarykidney    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a large N-terminal extracellular domain with five cadherin domains
  • a single membrane-spanning domain
  • a small, highly conserved C-terminal cytoplasmic domain
  • conjugated GlycoP
    HOMOLOGY
    interspecies ortholog to murine Cdh9
    ortholog to rattus Cdh9
    Homologene
    FAMILY
  • cadherin superfamily
  • CATEGORY adhesion
    SUBCELLULAR LOCALIZATION     plasma membrane
    text type I membrane protein
    basic FUNCTION
  • involved in homophilic cell adhesion
  • mediate calcium-dependent cell–cell adhesion
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Ca2+
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to autism spectrum disorders
    Variant & Polymorphism SNP rs4307059 increasing the risk of autism spectrum disorder
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS