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FLASH GENE
Symbol CDH9 contributors: mct - updated : 15-09-2009
HGNC name cadherin 9, type 2 (T1-cadherin)
HGNC id 1768
Location 5p14.1      Physical location : 26.880.708 - 27.038.689
Synonym name
  • cadherin-9
  • T1-cadherin
    • Synonym symbol(s) MGC125386
    DNA
    TYPE functioning gene
    STRUCTURE 157.98 kb     12 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    12 - 3075 - 789 - 2009 19404256
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrain    
    Urinarykidney    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a large N-terminal extracellular domain with five cadherin domains
  • a single membrane-spanning domain
  • a small, highly conserved C-terminal cytoplasmic domain
    • conjugated GlycoP
    HOMOLOGY
    interspecies ortholog to murine Cdh9
    ortholog to rattus Cdh9
    Homologene
    FAMILY
  • cadherin superfamily
    • CATEGORY adhesion
    SUBCELLULAR LOCALIZATION     plasma membrane
    text type I membrane protein
    basic FUNCTION
  • involved in homophilic cell adhesion
  • mediate calcium-dependent cell–cell adhesion
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Ca2+
    • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to autism spectrum disorders
    Variant & Polymorphism SNP rs4307059 increasing the risk of autism spectrum disorder
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS