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FLASH GENE
Symbol CDH24 contributors: - updated : 26-07-2005
HGNC name cadherin-like 24
HGNC id 14265
Location 14q11.2      Physical location : 23.516.270 - 23.526.747
Synonym symbol(s) CDH11L, FLJ25193
DNA
TYPE functioning gene
STRUCTURE 8.00 kb     12 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
ABHD4 14q11.1 abhydrolase domain containing 4 OR6J1P 14p12 olfactory receptor, family 6, subfamily J, member 1 pseudogene RPL26P2 14 ribosomal protein L26 pseudogene 2 LOC390461 14 similar to olfactory receptor C6 OXA1L 14q11.2 oxidase (cytochrome c) assembly 1-like SLC7A7 14q11.2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 MRPL52 14q11.2 mitochondrial ribosomal protein L52 MMP14 14q11.2 matrix metalloproteinase 14 (membrane-inserted) LRP10 14q11.2 low density lipoprotein receptor-related protein 10 FLJ38964 14q11.2 hypothetical protein FLJ38964 RNPC4 14q11.2 RNA-binding region (RNP1, RRM) containing 4 SKB1 14q11.2-q21 SKB1 homolog (S. pombe) C14orf94 14q11.1 chromosome 14 open reading frame 94 JUB 14q11.2 jub, ajuba homolog (Xenopus laevis) C14orf93 14q11.1 chromosome 14 open reading frame 93 PSMB5 14q11.2 proteasome (prosome, macropain) subunit, beta type, 5 LOC122706 14q11.2 similar to RIKEN cDNA 5830406J20 CDH24 14q11.2 cadherin-like 24 ACINUS 14q11.2 apoptotic chromatin condensation inducer in the nucleus C14orf119 14q11.2 chromosome 14 open reading frame 119 CEBPE 14q11.2 CCAAT/enhancer binding protein (C/EBP), epsilon SLC7A8 14q11.2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 RPL39P2 14 ribosomal protein L39 pseudogene 2 HMGN2P 14 high-mobility group nucleosomal binding domain 2 pseudogene KIAA1443 14q11.2 KIAA1443 LOC90673 BCL2L2 14q11.2-q12 BCL2-like 2 PABPN1 14q11.2-q13 poly(A) binding protein, nuclear 1 SLC22A17 14q11.2 solute carrier family 22 (organic cation transporter), member 17 EFS 14q11.2-q12 embryonal Fyn-associated substrate IL17E 14q11.2 interleukin 17E CKLFSF5 14q11.2 chemokine-like factor super family 5 MYH6 14q11.2 myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) MYH7 14q11.2 myosin, heavy polypeptide 7, cardiac muscle, beta C14orf120 14q11.2 chromosome 14 open reading frame 120
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- splicing 2873 87 819 - Katafiasz
- splicing 2759 83 781 - Katafiasz
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivefemale systemuteruscervix predominantly
 female systembreastmammary gland highly
Respiratoryrespiratory tractlarynx  moderately
Urinarybladder   moderately
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Nervousperipherous   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • five cadherin domains
  • conjugated GlycoP
    HOMOLOGY
    interspecies ortholog to murine Cdh24
    Homologene
    FAMILY
    CATEGORY adhesion
    SUBCELLULAR LOCALIZATION     plasma membrane
    text type I membrane protein
    basic FUNCTION
  • acting as a calcium dependent cell adhesion protein
  • mediating strong cell-cell adhesion (homophilic cell adhesion)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Ca2+
  • protein
  • alpha-catenins
  • beta-catenins
  • delta-catenins
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS