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FLASH GENE
Symbol CDH20 contributors: - updated : 03-05-2005
HGNC name cadherin 20, type 2
HGNC id 1760
Location 18q22-q23      Physical location : 59.157.774 - 59.222.365
Synonym symbol(s) FLJ37047, CDH7L3
DNA
TYPE functioning gene
STRUCTURE 64.00 kb     11 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemtestis   
Visualeye    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscular    
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal, pregnancy
Text placenta, brain
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • N terminal hydrophobic domain
  • five extracellular cadherin repeats
  • four cysteines in the most proximal (MPED)
  • a transmembrane segment
  • a highly conserved cytoplasmic tail required for interactions
    • conjugated GlycoP
    HOMOLOGY
    interspecies ortholog to murine Cdh7
    Homologene
    FAMILY
  • cadherin superfamily of calcium dependent cell-cell adhesion glycoproteins
    • CATEGORY adhesion
    SUBCELLULAR LOCALIZATION     plasma membrane,junction,adherens
    basic FUNCTION
  • involved cell-cell or cell-ECM interactions
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Ca2+
    • protein
  • hemophilic, calcium dependent interactions
  • interacting by its C terminus with the cytoskeleton via beta-catenin
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS