| basic FUNCTION
| SLAMF1, CD48, CD84, CD244, LY9, SLAMF6, SLAMF7 play an essential and non-redundant role in the control of humoral immune responses  |
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important immunomodulatory receptor with roles in cytotoxicity, humoral immunity, autoimmunity, cell survival, lymphocyte development, and cell adhesion |
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negatively regulates IgE high-affinity receptor signaling in human mast cells |
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natural killer T (NKT) cells and innate CD8(+) T cell development can be regulated in a SAP-dependent and -independent fashion by SLAMF receptors, in which SLAMF1, SLAMF6, and SLAMF8 affect development of NKT cells, and CD84, SLAMF7, and SLAMF8 affect the development of innate CD8(+) T cells |
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is dispensable for thrombus formation and stabilization, indicating that its deficiency may be functionally compensated by other receptors or that it may be important for platelet functions different from platelet-platelet interactions |
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central role for germinal center (GC) B cell-specific CD84 and SLAMF6 expression in maintaining B cell tolerance in GCs and in preventing autoimmunity |
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SLAMF1, CD84, and SLAMF6 are important negative regulators of humoral immune response, consistent with the notion that SLAM family receptors have dual functions in immune responses |
