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FLASH GENE
Symbol CD2BP2 contributors: - updated : 11-01-2005
HGNC name CD2 antigen (cytoplasmic tail) binding protein 2
HGNC id 1656
Location 16p11.2      Physical location : 30.362.087 - 30.366.682
Synonym symbol(s) FWP010
DNA
TYPE functioning gene
STRUCTURE 2.00 kb     7 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain    
Respiratorylung    
cell lineage
cell lines J77 Jurkat and COS-7
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a GYF domain
  • a consensus site for tyrosine phosphorylation
    • HOMOLOGY
    interspecies homolog to murine Cd2bp2
    Homologene
    FAMILY
    CATEGORY antigen
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • may mediate, through its GYF domain, the protein-protein interactions within the spliceosome
  • enhances IL2 production on crosslinking of CD2
    • CELLULAR PROCESS nucleotide, RNA splicing
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein interacts with the cytoplasmic tail of CD2
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS