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FLASH GENE
Symbol CD101 contributors: mct/ - updated : 19-07-2008
HGNC name CD101 molecule
HGNC id 5949
Location 1p13.1      Physical location : 117.544.381 - 117.579.166
Synonym name
  • leukocyte surface protein V7
  • immunoglobulin superfamily, member 2
  • Glu-Trp-Ile EWI motif-containing protein 101
  • CD101 antigen
  • Synonym symbol(s) V7, LSPV7, IGSF2, EWI101
    DNA
    TYPE functioning gene
    STRUCTURE 34.79 kb     10 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    10 - 3547 - 1021 - Meyer (2005)
    EXPRESSION
    Type restricted
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart    
    Lymphoid/Immunespleen    
    Reproductivefemale systemovary   
    Respiratoryrespiratory tractlarynx   
     respiratory tracttrachea   
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / Hematopoieticbone marrow   
    Lymphoid    
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Blood/Hematopoieticgranulocyte
    Blood/Hematopoieticmonocyte
    Lymphoid/Immunelymphocyte
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES Hydrophobic
    STRUCTURE
    motifs/domains
  • seven pairs of cysteine in the extracellular domain, suggestive of Ig-like domain
  • 20AA hydrophobic signal
  • 42AA cytoplasmic domain
  • six immunoglobulin-like c2-type domains
  • conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY
  • immunoglobulin superfamily
  • CATEGORY immunity/defense
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum
    intracellular,cytoplasm,organelle,Golgi
    text type I integral membrane protein, endoplasmic reticulum and trans-golgi network
    basic FUNCTION
  • playing a role in TCR/CD3 mediated cell interaction
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS