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FLASH GENE
Symbol CCT6B contributors: mct - updated : 22-03-2008
HGNC name chaperonin containing TCP1, subunit 6B (zeta 2)
HGNC id 1621
Location 17q11.2-q12      Physical location : 33.254.877 - 33.288.528
Synonym name
  • CCT-zeta-like
  • T-complex protein 1, zeta-2 subunit
  • TCP-1-zeta-like
  • chaperonin containing TCP1, subunit 6B
  • testis-specific Tcp20
  • Synonym symbol(s) CCT-zeta-2, CCTZ-2, Cctz2, TCP-1-zeta-2, TSA303
    DNA
    TYPE functioning gene
    STRUCTURE 33.00 kb     14 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked   status provisional
    Map see IMC1@
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    14 - 1828 - 530 - Stirling (2006)
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Reproductivemale systemtestis  specific
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    mono polymer heteromer
    HOMOLOGY
    interspecies homolog to yeast S.cerevisiae TCP20
    Homologene
    FAMILY TF55/TCP-1 family
    CATEGORY chaperone/stress
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • mediating ATP-dependent monomeric protein folding
  • molecular chaperone that assists the folding of proteins upon ATP hydrolysis
  • may have specific functions in the folding of testicular proteins and for interactions with testicular molecular chaperones
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component component of a heterooligomeric complex
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS