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FLASH GENE
Symbol CCL13 contributors: - updated : 22-04-2006
HGNC name chemokine (C-C motif) ligand 13
HGNC id 10611
Location 17q11.2      Physical location : 32.683.470 - 32.685.628
Genatlas name see IMC1@
Synonym name small inducible cytokine subfamily A (Cys-Cys), member 13
Synonym symbol(s) MCP4, NCC1, SCYL1, SCYA13, MGC17134
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
STRUCTURE 2.00 kb     3 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinelarge intestinecolon  
Endocrinepancreas    
Nervousbrain    
Respiratorylung    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectivebone   
Lymphoid    
cells
SystemCellPubmedSpeciesStageRna symbol
 digestive
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated GlycoP
HOMOLOGY
Homologene
FAMILY intercrine beta family (small cytokine C-C) (chemokine CC)
CATEGORY signaling cytokine
SUBCELLULAR LOCALIZATION extracellular
    plasma membrane
basic FUNCTION
  • chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils
  • involved in the accumulation of eosinophils characteristic for eosinophilic inflammatory diseases
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS inflammation
    text inflammatory response
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other can bind heparin
    REGULATION
    induced by TNF-alpha
    interleukin-1
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS