Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol CASKIN2 contributors: - updated : 27-08-2005
HGNC name CASK interacting protein 2
HGNC id 18200
Location 17q25.3      Physical location : 73.496.342 - 73.511.627
Synonym symbol(s) FLJ21609, KIAA1139, CAROM
DNA
TYPE functioning gene
STRUCTURE 15.00 kb     20 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver   moderately
Endocrinepancreas   moderately
Nervousbrain   moderately
Reproductivemale systemprostate  moderately
Respiratorylung   moderately
Urinarykidney   moderately
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • an N-terminal calcium/calmodulin-dependent protein (CaM) kinase domain
  • central PSD-95,Dlg,and ZO-1/2 domain (PDZ)
  • a coiled-coil domain
  • two Src homology 3 (SH3) domains
  • a C-terminal guanylate kinase sequence
  • HOMOLOGY
    interspecies ortholog to murine Caskin2
    Homologene
    FAMILY
    CATEGORY adaptor
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION may be linking CASK to the cytoskeleton
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • binding to Mint1, Velis
  • interacting with CASK by its calmodulin kinase domain
  • interacting with MAGI1 by the fifth PDZ domain of MAGI1
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS