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FLASH GENE
Symbol CASC2 contributors: mct - updated : 04-11-2020
HGNC name cancer susceptibility candidate 2
HGNC id 22933
Location 10q26.11      Physical location : 119.806.331 - 119.969.659
Synonym name chromosome 10 open reading frame 5
Synonym symbol(s) C10orf5, MGC117219
DNA
TYPE small rna
STRUCTURE 163.00 kb     7 Exon(s)
MAPPING cloned Y linked N status provisional
Map cen - D10S1877 - D10S221 - D10S1693 - D10S610 - [D10S1236 - D10S190 - D10S1230 ] - D10S1213 - D10S1656 - qter
Authors Baldinu (04)
Text [CASC2 ]
RNA
TRANSCRIPTS type untranslated
EXPRESSION
Rna function
  • HNF1A positively regulated CASC2 expression
  • CASC2 might be a useful biomarker of hepatocellular carcinoma (HCC)
  • Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    Text eye
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    mono polymer homomer
    HOMOLOGY
    Homologene
    FAMILY thiolase family
    CATEGORY tumor suppressor
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --low  
    isoform CASC2a, in endometrial cancer
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS