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FLASH GENE
Symbol CAMK1D contributors: mct - updated : 05-01-2017
HGNC name calcium/calmodulin-dependent protein kinase ID
HGNC id 19341
Location 10p13      Physical location : 12.391.582 - 12.871.731
Synonym name CamKI-like protein kinase
Synonym symbol(s) CKLiK
DNA
TYPE functioning gene
STRUCTURE 480.00 kb     0 Exon(s)
MAPPING cloned Y linked N status provisional
Physical map
LOC389938 10 similar to SI:dZ211O13.2 (novel protein) CUGBP2 10p13-p14 CUG triplet repeat, RNA binding protein 2 USP6NL 10p13 USP6 N-terminal like ECHDC3 10p14 enoyl Coenzyme A hydratase domain containing 3 C10orf47 10p14 chromosome 10 open reading frame 47 UPF2 10p14-p13 UPF2 regulator of nonsense transcripts homolog (yeast) DHTKD1 10p14 dehydrogenase E1 and transketolase domain containing 1 SEC61A2 10p14 dehydrogenase E1 and transketolase domain containing 1 NUDT5 10p14-p13 nudix (nucleoside diphosphate linked moiety X)-type motif 5 C10orf7 10p13 chromosome 10 open reading frame 7 CAMK1D 10p13 calcium/calmodulin-dependent protein kinase ID DKFZP761F241 10p14 hypothetical protein DKFZp761F241 LOC389939 10 similar to ribosomal protein L5 OPTN 10p14 optineurin MCM10 10p13 MCM10 minichromosome maintenance deficient 10 (S. cerevisiae) LOC221044 10p14 hypothetical protein BC018068 PHYH 10p15-p14 phytanoyl-CoA hydroxylase (Refsum disease) SEPHS1 10p14 selenophosphate synthetase 1 C10orf30 10p14 chromosome 10 open reading frame 30 PRPF18 10p12.33 PRP18 pre-mRNA processing factor 18 homolog (yeast) FLJ10210 C10orf45 10p14 chromosome 10 open reading frame 45
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 1579 40 357 polymorphonuclear leukocytes Ishikawa
- - 2235 42 385 polymorphonuclear leukocytes Ishikawa
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoietic    
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticleukocyte
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • serine/threonine kinase motif
  • tyrosine kinase motif
  • calmodulin-binding domain
  • autoinhibitory domain
  • HOMOLOGY
    intraspecies homolog to CAMK1
    Homologene
    FAMILY Ca2+/calmodulin-dependent kinase family
    CATEGORY enzyme , receptor membrane serine/threonine tyrosine kinase
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • serine/threonine kinase activity
  • involved in protein amino-acid phosphorylation
  • may play a role in Ca2+-mediated regulation of granulocyte functions
  • induces ERK MAP kinase activation
  • can directly phosphorylate CREM and activate CREB
  • CELLULAR PROCESS protein
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    part of the chemokine signal transduction pathway
    a component
    INTERACTION
    DNA
    RNA
    small molecule nucleotide,
  • ATP binding
  • protein
  • NDEL1 enzyme activity was found to be associated with CAMK1D, MAGI2, CCDC25, and GABGR3
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS