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FLASH GENE
Symbol CAMK1D contributors: mct - updated : 05-01-2017
HGNC name calcium/calmodulin-dependent protein kinase ID
HGNC id 19341
Location 10p13      Physical location : 12.391.582 - 12.871.731
Synonym name CamKI-like protein kinase
Synonym symbol(s) CKLiK
DNA
TYPE functioning gene
STRUCTURE 480.00 kb     0 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 1579 40 357 polymorphonuclear leukocytes Ishikawa
- - 2235 42 385 polymorphonuclear leukocytes Ishikawa
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoietic    
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticleukocyte
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • serine/threonine kinase motif
  • tyrosine kinase motif
  • calmodulin-binding domain
  • autoinhibitory domain
  • HOMOLOGY
    intraspecies homolog to CAMK1
    Homologene
    FAMILY Ca2+/calmodulin-dependent kinase family
    CATEGORY enzyme , receptor membrane serine/threonine tyrosine kinase
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • serine/threonine kinase activity
  • involved in protein amino-acid phosphorylation
  • may play a role in Ca2+-mediated regulation of granulocyte functions
  • induces ERK MAP kinase activation
  • can directly phosphorylate CREM and activate CREB
  • CELLULAR PROCESS protein
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    part of the chemokine signal transduction pathway
    a component
    INTERACTION
    DNA
    RNA
    small molecule nucleotide,
  • ATP binding
  • protein
  • NDEL1 enzyme activity was found to be associated with CAMK1D, MAGI2, CCDC25, and GABGR3
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS